Ethyl 5-bromofuran-2-carboxylate - Names and Identifiers
Ethyl 5-bromofuran-2-carboxylate - Physico-chemical Properties
Molecular Formula | C7H7BrO3
|
Molar Mass | 219.03 |
Density | 1.533±0.06 g/cm3(Predicted) |
Melting Point | 17 °C |
Boling Point | 234 °C |
Flash Point | 100.9°C |
Vapor Presure | 0.0325mmHg at 25°C |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Refractive Index | 1.52 |
Ethyl 5-bromofuran-2-carboxylate - Introduction
Ethyl 5-bromofuran-2-carboxylate, chemical formula C7H7BrO3, is an organic compound. The following describes its nature, use, preparation and safety information:
Nature:
-Appearance: Ethyl 5-bromofuran-2-carboxylate is a colorless to pale yellow liquid.
-Melting point:-36°C.
-Boiling point: 158-160°C.
-Solubility: Soluble in organic solvents such as ethanol and ether, difficult to dissolve in water.
Use:
-Ethyl 5-bromofuran-2-carboxylate is an important organic synthesis intermediate, widely used in the synthesis of drugs, pesticides and other organic compounds.
-It can be used to synthesize biologically active compounds, such as antiviral, antitumor and antibacterial agents.
Preparation Method:
- ethyl 5-bromofuran-2-carboxylate can be obtained by reacting ethyl furan-2-carboxylate with bromide.
-The specific preparation method is to react ethyl furan-2-formate with the nucleophilic reagent sodium bromide or 2-bromohydrated alcohol in an inert atmosphere, and react in an appropriate solvent to obtain ethyl 5-bromofuan-2-carboxylate.
Safety Information:
-Ethyl 5-bromofuran-2-carboxylate exposure and inhalation may cause health hazards, and long-term or large-scale exposure should be avoided.
-Wear appropriate personal protective equipment such as goggles, protective gloves and protective clothing during operation.
-Avoid contact with skin, eyes and respiratory tract. If contact occurs, rinse the corresponding area with plenty of water immediately and seek medical help.
-Waste shall be disposed of in accordance with local regulations and shall not be discharged directly into the natural environment.
Last Update:2024-04-09 15:17:58